2025’s 5 Best Weight Loss Supplement

Did you know that most Weight Loss Supplements don’t work? We’ll help you pick one that does.

Charles Bloom

Dr. Bloom is a certified health coach based in the tranquil surroundings of California. His core philosophy revolves around nurturing healthy habits that empower individuals to lead life to its fullest potential.

[email protected]

The market is overflowing with various diet supplements and weight loss pill. Sadly most of them are completely useless. There are some that have been peer reviewed and clinically studied but finding which ones are actually effective is almost impossible.

However, if you manage to find a few effective solutions out there the results are truly amazing.

By speeding up your metabolic rate these solutions will cause dramatic weight loss while giving you an enormous energy boost that lasts out the day. You’ll feel how your mood changes, making you strong enough to keep away from that emotional junk food. The best supplements will even suppress your appetite, stopping constant cravings.

In fact, the clinically proven supplements out there will help you lose weight fast and easily.

We have researched all of the clinically proven supplements out there to find the most effective, safe and fat burning supplement out there.

You’ll find the most effective weight-loss pills on the market below.

TOP 5 WEIGHT LOSS SUPPLEMENTS OF 2025

We've compiled a list of what we've found to be the top five products in this category, on the market today.

Updated: June 19, 2025

3647 votes

9.8/10

DOCTORS RATING

A+

FINAL GRADE

Quality Of Ingredients

8.4 AVG.

9.7/10

Medically Proven Effect

8.2 AVG.

9.8/10

Health Benefits

8.3 AVG.

9.9/10

Customer Satisfaction

7.8 AVG.

9.8/10

Money Back Guarantee

7.9 AVG.

9.7/10

PROS

  • Boosts your metabolism significantly
  • Melts away body fat quickly
  • Gives you a major energy boost
  • Keeps your hunger and cravings in check
  • Helps maintain balanced blood sugar levels
  • Packed with immune-boosting antioxidants
  • Boosts your self-confidence
  • Delivers lasting benefits for steady weight loss
  • Comes with a 30-day money-back guarantee
  • No harmful side effects to worry about
  • Enjoy free shipping when you purchase 2 or more bottles
  • Supported by multiple clinical studies proving its effectiveness
  • Active ingredients are backed by scientific research
  • 98% of our customers are satisfied with the results
  • No need to commit to an auto-shipping delivery plan

CONS

  • Due to its immense popularity Berberine is often out of stock

Our Key Takeaways

True Tone Berberine stood out as our top choice among various well-known weight loss supplements. It's no surprise considering it delivered rapid and safe weight loss results for all our testers, even those with substantial weight to shed.

An impressive 98% of users were satisfied with True Tone Berberine, reporting not only effortless attainment of their target weight but also successful weight maintenance.

What sets True Tone Berberine apart is its comprehensive approach to weight loss. Unlike some supplements that offer limited benefits, this product addresses common dieting challenges such as overeating and cravings for high-carb, sugary foods.

Our testers unanimously agreed that they no longer felt the urge to snack between meals, and their reduced appetite resulted in consuming fewer calories throughout the day, all without experiencing hunger pangs. Plus, the increased energy levels provided by these gummies encouraged more frequent and extended workout sessions.

It's no surprise that True Tone Berberine is a product of True Tone, a well-established and trusted name in the US health supplement industry. These gummies are manufactured in a state-of-the-art facility that strictly adheres to safety regulations.

The company's confidence in its product is evident through its hassle-free 60-day money-back guarantee for True Tone Berberine. Our extensive research and firsthand experience with its remarkable benefits leave no doubt in our minds - True Tone Berberine deserves the title of the best weight loss supplement of 2025!

2166 votes

9.3/10

DOCTORS RATING

A-

FINAL GRADE

Quality Of Ingredients

8.3 AVG.

9.1/10

Medically Proven Effect

8.1 AVG.

8.8/10

Health Benefits

8.2 AVG.

8.5/10

Customer Satisfaction

7.9 AVG.

9.2/10

Money Back Guarantee

7.9 AVG.

9.6/10

PROS

  • Slim Plus Keto ACV Gummies full formula is listed
  • It uses good quality ingredients

CONS

  • Slim Plus Keto ACV Gummies is exclusively available for purchase online
  • Does not offer free samples
  • Has not received FDA approval

Our Key Takeaways

When compared to numerous other weight loss supplements available, Slim Plus Keto ACV Gummies does seem to have a relatively good reputation and various purchasing options. Nevertheless, it may not live up to the manufacturer's claims of effectiveness, and there is limited evidence from clinical studies to support its speed and efficiency in producing results.

982 votes

9.0/10

DOCTORS RATING

B

FINAL GRADE

Quality Of Ingredients

7.8 AVG.

8.2/10

Medically Proven Effect

8.1 AVG.

7.9/10

Health Benefits

8.2 AVG.

8.5/10

Customer Satisfaction

7.9 AVG.

8.4/10

Money Back Guarantee

7.9 AVG.

8.2/10

PROS

  • The primary active ingredient in BioLush - Keto Gummies Private is disclosed
  • Some clinical studies have been conducted

CONS

  • Users may need to consider making lifestyle adjustments to reap the full benefits of BioLush - Keto Gummies
  • It's worth noting that BioLush - Keto Gummies Private come with a high price tag
  • Keep in mind that the free trial is associated with an auto-ship program
  • Additionally, the full formula details are not disclosed
  • There is limited information available online about the manufacturer

Our Key Takeaways

Next up is BioLush - Keto Gummies, a product that has been gaining attention and establishing itself as a significant player in the weight loss and diet industry. While it may not fully live up to all the extravagant claims some make about it, it is indeed a potent supplement for weight loss. Although additional scientific evidence would be reassuring, it's worth noting that many users are giving it a positive endorsement as a reliable choice for achieving ketosis. If you're in search of a weight loss supplement, BioLush - Keto Gummies is certainly a strong option worth considering.

730 votes

8.9/10

DOCTORS RATING

B-

FINAL GRADE

Quality Of Ingredients

7.2 AVG.

7.5/10

Medically Proven Effect

7.9 AVG.

7.7/10

Health Benefits

8.2 AVG.

8.2/10

Customer Satisfaction

7.6 AVG.

7.9/10

Money Back Guarantee

7.9 AVG.

8/10

PROS

  • Simply Lean Keto + ACV Gummies provides a list of its main active ingredients
  • They offer discounts for bulk purchases

CONS

  • Simply Lean Keto + ACV Gummies appears to have a high price of $89.95
  • There is a lack of clinical trial studies provided
  • It's important to note that this product does not have FDA approval

Our Key Takeaways

The fourth-best keto weight loss supplement on our list is Simply Lean Keto + ACV. It received high ratings in ingredient safety, value, effectiveness, return policy, and customer satisfaction, with each category scoring over 8 out of 10. It's safe to conclude that Simply Lean Keto + ACV is a reliable brand for keto weight loss gummies, offering all the primary benefits found in other top brands. With an impressive score of 83%, we confidently endorse Simply Lean Keto + ACV for those seeking a safe and side-effect-free way to lose weight. It's worth noting that while the majority had a positive experience, a few customers mentioned encountering some challenges with the return process, albeit in rare cases of refund requests.

397 votes

7.9/10

DOCTORS RATING

B-

FINAL GRADE

Quality Of Ingredients

7.3 AVG.

6.9/10

Medically Proven Effect

7.0 AVG.

7.3/10

Health Benefits

7.1 AVG.

7.7/10

Customer Satisfaction

7.9 AVG.

7.2/10

Money Back Guarantee

7.9 AVG.

8.4/10

PROS

  • In our own test it showed some effectiveness
  • Decent Price Point

CONS

  • Not FDA Approved
  • No Money Back Guarantee
  • Expensive Shipping Fee
  • Not Clinically Studied

Our Key Takeaways

Given the relatively steep price of Destiny Keto + ACV Gummies, it would be beneficial if the manufacturer of this weight loss supplement offered additional details about their company and shared results from clinical testing conducted on the formula. Doing so would not only substantiate the claims presented on their website but also help rationalize the somewhat higher cost associated with the brand.

TOP WEIGHT LOSS SUPPLEMENT OF 2025

3647 votes

9.8/10

DOCTORS RATING

A+

FINAL GRADE

What Are Keto ACV Gummies?

Keto ACV gummies are delicious candies made with apple cider vinegar (ACV) designed for individuals following a specific diet called the ketogenic (keto) diet.

These keto ACV products have gained recognition on popular television programs such as Shark Tank on ABC, various news broadcasts, and renowned shows like Dr. Oz and even Oprah!

It's important to note that these shows typically do not endorse specific keto products. That's where we come in - we review and rank the top products to ensure you have the right tools for your weight loss journey, particularly with these sought-after belly fat burners.

We've also come across claims* suggesting that many celebrities, including Kelly Clarkson, Dolly Parton, Randy Jackson, and Melissa McCarthy, have incorporated different types of keto supplements and diet plans to achieve remarkable transformations in their physical shape! (Please see the expanded list below.)

These gummies indeed contain ACV, which has a potent taste. To make it more palatable and give it a gummy texture, they blend it with other ingredients like jelly, sugar, and flavorings. People favor them because they offer an easy way to consume healthy fats and support their keto diet, ultimately aiding in weight management.

Who Are Keto ACV Gummies Good For?

Keto ACV gummies might be a suitable choice for:

How Might Keto ACV Gummies Help You?

The effects of taking these gummies can vary from person to person. After analyzing user reviews, our team has compiled the benefits that most individuals tend to experience after incorporating keto ACV gummies into their daily routine over time:

Within 1 - 2 Months:

Within 3 - 6 Months:

Beyond 6 Months:

What To Avoid

Bad Taste:

It's preferable for gummies to have natural fruit flavoring to make them more enjoyable, as regular apple cider vinegar has a strong taste.

Gelatin:

Gummies containing gelatin should be avoided, as they can cause bloating, stomach discomfort, or excessive burping for some individuals. Look for gummies containing pectin, a beneficial type of dietary fiber.

Fake Celebrity Reviews:

Beware of scams and purchase legitimate products from reputable sources. If you come across a website claiming that a specific celebrity endorses a product, exercise caution.

15 Celebrities Who've Tried the Keto Diet

According to everydayhealth.com*, here is a list of the top 15 celebrities who have experimented with the keto diet:

Final Verdict

3647 votes

9.8/10

DOCTORS RATING

A+

FINAL GRADE

Reference

  1. Youm, Yun-Hee et al. "Inhibition of NLRP3 Inflammasome-Mediated Inflammatory Disease by β-Hydroxybutyrate Ketone Metabolite." Published in Nature Medicine, Volume 21, Issue 3, 2015. Read More
  2. Sanya, E. O et al. "Magnesium Supplementation's Impact on Antiseizure Properties of the Ketogenic Diet and Reduction of Lipid Dysmetabolism." Published in the West African Journal of Medicine, Volume 37, Issue 1, 2020. Read More
  3. Kim, Ju Young. "Effective Dietary Strategies for Weight Loss and Weight Maintenance." Published in the Journal of Obesity & Metabolic Syndrome, Volume 30, Issue 1, 2021. Read More
  4. Yao, Aliya et al. "Nutritional and Therapeutic Effects of D-β-Hydroxybutyrate Ketone Body." Published in Applied Microbiology and Biotechnology, Volume 105, Issues 16-17, 2021. Read More
  5. Tabrizi, Reza et al. "The Impact of Caffeine Intake on Weight Loss: A Comprehensive Review and Dose-Response Meta-Analysis of Randomized Controlled Trials." Published in Critical Reviews in Food Science and Nutrition, Volume 59, Issue 16, 2019. Read More
  6. Urtasun, Raquel et al. "Combining Apple Vinegar Drink with Bacillus Coagulans for Mitigating High Fat Diet-Induced Body Weight Gain, Insulin Resistance, and Hepatic Steatosis." Published in Nutrients, Volume 12, Issue 9, 2020. Read More
  7. Türközü, Duygu, and Nevin Şanlier. "L-theanine: A Distinctive Amino Acid in Tea, Its Metabolism, Health Benefits, and Safety." Published in Critical Reviews in Food Science and Nutrition, Volume 57, Issue 8, 2017. Read More
  8. Stefan, Matthew et al. "The Impact of Exogenous Beta-Hydroxybutyrate Salt Supplementation on Safety and Health Metrics in Adolescents." Published in Nutrients, Volume 13, Issue 3, 2021. Read More
  9. DiNicolantonio, James J, and James H O’Keefe. "Comparing Good Fats and Bad Fats: Evaluating Fatty Acids in their Role in Promoting Insulin Resistance, Inflammation, and Obesity." Published in Missouri Medicine, Volume 114, Issue 4, 2017. Read More
  10. Harvey, Cliff J D C et al. "Utilization of Nutritional Supplements to Induce Ketosis and Alleviate Symptoms Associated with Keto-Induction: A Narrative Review." Published in PeerJ, Volume 6, 2018. Read More
  11. Westerterp-Plantenga, Margriet S et al. "Weight Loss and Weight Maintenance in Relation to Routine Caffeine Intake and Green Tea Supplementation." Published in Obesity Research, Volume 13, Issue 7, 2005. Read More
  12. Depeint, Flore et al. "Mitochondrial Function and Toxicity: The B Vitamin Family's Role in Mitochondrial Energy Metabolism." Published in Chemico-Biological Interactions, Volume 163, Issues 1-2, 2006. Read More
  13. Kamei, Yasutomi et al. "Regulating Skeletal Muscle Function through Amino Acids." Published in Nutrients, Volume 12, Issue 1, 2020. Read More
  14. Wells, Jana et al. "Efficiency and Safety of a Ketogenic Diet for Children and Adolescents with Refractory Epilepsy - An Overview." Published in Nutrients, Volume 12, Issue 6, 2020. Read More
  15. "15 Notable Personalities Who Have Experimented with the Keto Diet." Read More